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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3ce29e4588340634d6232be190b649af12a3dc5116f2a8c3ad2f575a5d502094' 
  AND token = 'KDzDcr7IQACFVaEYgHBPKjw/5imuEb60e188qcIsOWo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}