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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9504d75cd8bfb9344bc95f59907e0e08feea2d1f71f3937960dab6e1f4705fbc' 
  AND token = 'efwf49j+qaj+Fr/CQdQAsLO9IPcg7EMCeU0J/G5+Q7w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}