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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4327c3c612c9bc527e479638f861072948a80e2ba9c0ece6197f7fe1be4a6ca8' 
  AND token = 'sbMd5r8QcG/wrfuHjDzzgeL2MDpxcGaMkT2Z4aAbswM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}