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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1a86abeaaed63c23c33ab63c6e06ca099e0c1d3b981866f5897d03f8ddfaa9ed' 
  AND token = '6y6WY0qgm+vas/2wpnhJXIgvs3Bs5lxMUuxnPig9aug=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}