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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c76e7200d19a80c3ad208c1cec9139415a834a1e65cc5c4c324d311fdd83c5ad' 
  AND token = 'M9EL7xA1Tu4WqLGUj07KTtqh0E8srjV3DKmwUVRAlHY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}