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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0756c9e3a4c0a278377b55c9950591f64808941c5a6798290b203f1d2e598c1e' 
  AND token = 'wR9wbRdJsHqm3aB+A6SWlDi1EACtNBo/iCBz3H+vuHA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}