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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '452617543f025efb815ccd480862bdb984457ae36e398c277ee6dbe1a2d96fc9' 
  AND token = 'de5QbOp7j3dXKh20A3TuIJKr4CG8utWka6axa+vZ4LA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}