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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '215651e7e81849e428ec81b2ba60481d25441ab88ce9e600ec052cc207a4aea0' 
  AND token = '3HlXNTOwjYvEwePAB/oiegDmK1NALPI427k7NS3Py3o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}