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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1438ab96b5a008eeb2a8d671e50d79f4491d5626be022e80a20612c26026c636' 
  AND token = 'K+Y+6aoTf0Z5g7LnlvBnShITk1xSdrsNKa8H2ALkh4A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}