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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f893819262836f29a75b449f03a19a05ac90e008d9d74ff0a5ac03d5f18fb21f' 
  AND token = 'C4Ny/A+/iBd90mn5mn/yrT2Lf9TejODE0aiUi2PE+oA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}