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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4e75a48b0242d04218fedecd4760e9d053eb80bd4177e6cfd64dc4249b537ee6' 
  AND token = 'Pru32drkM7p4ps/NF3A6Te5v0U03VVjq8za3/WnmoxE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}