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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5ce8b2b3742f18a958a79440f42375b58173c38cecf74a3da8c4bf8ef1511012' 
  AND token = 'inMhb2h00eAbhkZihARDNsiaAvkdyTjKUT4ykMLh5O8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}