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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8f93c1f2066827c8c69d81f71fd60962a3d8662a79a1fbd6478c85170b1d1b45' 
  AND token = '2KTCTaFqaS0bPeeNWZsykuE8XOde4Fgp4cQ9LVGUESM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}