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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b0fd4f2dcba5555e23016d00904ae9bdbd53402004929a724f508cda96c681da' 
  AND token = '/BRDZSY8SX9QWusWCzTq6cFG9N5w/dhAe1G0p5W1UbM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}