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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a4e2bf78148a413a0ccd252a10e6821417fe16114c63ea6fa9abc35481fb8e4a' 
  AND token = 'B5OM9rOWJ13JAL6jsu9L1+pafqSd13j4nnWAFBLkClg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}