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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '116161d4cd6be1cf69d2edf247c33a09a358084d37e62308a9ebf3d50c35e185' 
  AND token = 'C4r1hiyXqMjYR3MlIxthe7W+VhNFawt56QwcnEx7bSM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}