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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd1d6f706b43d91ace7ca77b4830bbe2378bf8f027bd1e9854c0d5ec755dda3be' 
  AND token = 'n92q0ZyEYCH6CBO4k3OA5zlrY0Bmg9BQ+vERqo1arMM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}