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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '26d9a15c1751f4a91235e52c7a1776a17342e273f49b104b8a5d0ec0fc8d6b3e' 
  AND token = '1hOCFsV0rXRC0C+vdfT/+nOeuDqZc/YnFpwDCX8W0E0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}