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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6b69af821bbf52407c00f2d61cc71eac40661e9b0dd96dbf336be139b8de32c0' 
  AND token = 'hVTPpqmfIBnR9pKlx4F6d4LkZI48ay9xYRFZSDIzhLI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}