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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '395e9729986ea6f836daf37cec248ac1f0879051982862e9842f2dffaf855d6a' 
  AND token = '7hugWYWwxk7YaWnIl/ux2ooZCO5gMtZvSs8woII4Izg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}