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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd3e6ba8fba058d0d500cbf4e7441c0b3cf326615240b41cee8d59e6024f303a6' 
  AND token = 'cNiEgJoNxKeD74V2d3NWmmaXxNgwJl6nWPAXTj66+as=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}