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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1303162946ae37e009ae8078ee7b7fa06c66771bbbc0505074bda3e7ca943a65' 
  AND token = 'k1krKT1XwRudiosFdTV++Oo68MM4CqKcXULzor2THK4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}