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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e57324aabde54e537505d76430d2c61536a2dc7d513e6124ade1d865b29f7a2a' 
  AND token = 'gVPBHUvSQ2WG84X4sAJ8iknGzJc2NUP1riWVbRxPwiw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}