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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '50ec660099cd7ca7b19589880ed890ff33cd9b0c3e7d5c77428aedffbe979026' 
  AND token = '1YHG2o8WDV0PMikX4E/MprAZLKx4WmyyApXbpEZRF/c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}