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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3b560e9e3b345123f4643cb5d3ee6cc069e3dfd487eba2f291327f12df5dd9f0' 
  AND token = '1XDAxZ4WqhxBeNbPTZV97fmZgA4wi+PqIWYH+teD1Ss=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}