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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '489251b4ee52dc316f7e917389beab8aa5de030750466a4dba9967876c505686' 
  AND token = 'k9giz6B72uSxq7TOt3aqdEVIJMU1rOqpgCn6aDKv0lQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}