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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '448818c583be4d1412fd3919371fa6ea742e9ff1c7bd7834004b33b2e165aa99' 
  AND token = '0dxqGasJTlCujvK0un4UfYvfVmbXuqaVUn74ejO59j4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}