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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'abe15383603b56930ac74da2610b56e2825e3952eba10f5a7c6e923ebd4beb8b' 
  AND token = 'XNMJL7ZXzNq2EIRZ3IsSasSK1IOhU8+KHd/FKP/3GYo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}