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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '29c98c1767c7b7a213a15014cb0a90fe03dfafdb4260db81a0db150e357ec3ff' 
  AND token = 'A/5fbo03FUz64+3V1pv9TTtliLNbGDTTPf+DPiMcQfg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}