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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'dd7780d1f871f4b8cafa2a16f040d6dc5af1cc5050b9a06251c783f2e7ff4c00' 
  AND token = 'MpShV4fTSaWum4rLWYd1cnL+2yBLNWNK8B6xn18DROg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}