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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f16909e8ab94b2dd7ae9b6f614c241505c09ddf5a0bdef724625cd604db58daf' 
  AND token = 'N05XKeBx+DBOrg43vp/hsBlp6pf+8PaHN9XycQQhZV8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}