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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '179bee3ba86a4f324eff1e6691988c073a1c71d57f357219dca185cc3f9f6130' 
  AND token = 'GnzRiOuUh7uifFVRRYYb3672LnIpP+C58AYeeMki7HI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}