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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '49b64f262f6a349614fabd5a80a092ef2e0f7f7d095de3eb1a5613f1aedd65f4' 
  AND token = 'RnuYuN8jWqsRDB4V2Ubt4Xmh/foAtEHp2znd1Md2yl8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}