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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9d927d63e80cdf29e089f6cd70d82386cf8acd2c40b874788c859f36ee99d136' 
  AND token = 'RDNZPDMKlJ5Cck3KFSS0fI4vKCDLE9YeVwT8p/41M0M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}