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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9bb246728c042a1792e35c77fad8665b32c68803bcec3d11c4664675013e6f60' 
  AND token = '6ppbKpvlMFXKuX3HI4RhVKxYQU4Mc534xWjbo+8TeWQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}