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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '67154286a5c0bbb0c4201dc4f8b72e8e6f1f5abd36d45a364d58551d982e4b4b' 
  AND token = 'ZDpAtei7PteQcNYsP9ou+Ghu5TjCVNHGfH3oYpMbQwE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}