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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '291069df6695659c66194b2a71142224633b9603663385273a747e783dc0e63a' 
  AND token = 'dgOaJ0VifLVhtQVQDom8yorPpaz4UWVO6HYk5gFFypo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}