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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'acf7579a3dee61a932f89d970d1f19bf71f8357e840400a539eccdab6e1d135d' 
  AND token = 'Yktm93GTAC8cjakAhFOwyR/b62dQMHWZuyIPB4Qeimo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}