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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8f693b3c7a343983d9e5cbccc1d8d528c9b40dd05b5c72aad136816b16c662cc' 
  AND token = 'opA0gPSSF6Ta6vQno1jaQX7uS0InQjP0/1wMFkIoOHM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}