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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3c2d3df6c67464158f1e07d61f85374e69ebbd9fbe5e3c73a75172c72d6936ae' 
  AND token = 'MRtc3sLDgacmrGtQeppy2ud9YxIam6gBrvlUL1pHIpM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}