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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cbfcbb0f2224ccb5cfb476440081832952f5576d7e38ebd767d25fcc2c33fb40' 
  AND token = 'bdM+sc8Bm2QYg7mDwBt+QmJbur71TbTZuNgxBUiXKWg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}