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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4775b5a6dac9b9983f11ae96f5a037610c949aa3bafb23808d0d408d3d050338' 
  AND token = 'xaixHZDstLulfXGfBIWfGDQdj88KexDR9HxMymoDFes=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}