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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '22ac96e6ef62230d4f330c679a43434d9ac48c5f8751e0266b42aa8a450bc5f4' 
  AND token = 'Ji8/sJ+/4P0Qi38ql2Wtd4PfcO3JHYWE8kkW22k8uZQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}