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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9df43e404cd2ec134f5f000c67c75e70536edf5e57bae91df747b5b5f61df710' 
  AND token = 'oSyLXXNHToGl6yd0EwWO4sBhQwBdflgiRgBWY1QP6hA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}