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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'dad89df6ad756b60dd695dcb7df831a50d055a36b9b0e6c07a0b093b727d46d8' 
  AND token = 'pfprKSnoEGS3r+UwTjmJgOOpaeRKB4xQ21CvcSTROsg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}