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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3731be506a0f7520bacfe3310d13a32bd6367e5171ab5f42074336784d088fd4' 
  AND token = 'tZWm4EKYdaiEBNpOKoKvAj1fg6XQUK7NPS6yIdwohpU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}