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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a99ccc03cc45f2f3877b5fa051ed5cec0b150026889da781bddb7223bfa7ff86' 
  AND token = 'DTYDWqJn3QLmN7S3V7KoFeOE+1+p3w05lcy+Q1FKmGI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}