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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e2635d2de3576e79ddfd74aa53ec9699125003e624552651058864a906bdfa07' 
  AND token = '5Y4YGKnvG+xKs8CiKdLp6nA5i8EG5I+hJmIfiZAcxpQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}