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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '446c59319ceeef94882c77f55253db37c7e0879b6c96a1b4af7021efcc268ae3' 
  AND token = 'WXVpaTvoGwfEp9j8UXPrwZ0ddb8RCCFbr65hmPV3yVA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}