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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e2f472a6f4a8cf2eaba03b00ca80f716f7e154bb327cc287a6c8205dd8d31b14' 
  AND token = '0ibbL9eVUutICVVOOgrLF6iXnEoAvnWdEpr+XgRQHcM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}